Hypersensitivity reaction to Calcium levofolinate – a clinical case.
Resumo
The frequency of allergic reactions to calcium levofolinate is unknown and anaphylactic reactions are described as very rare.
The authors present the case of a 43-year-old male allergic to levofolinate with a positive oral provocation test.
Clinicians should be aware of hypersensitivity reaction with calcium-levofolinate, especially when is administered concomitantly with oxaliplatin, despite its lower risk to cause hypersensitivity reactions. Furthermore, the similar signs and symptoms associated to the hypersensitivity reactions of each agent, highlight the importance of having a specialized allergist team for to make a prompt diagnose of the causative agent in order to prevent patient harm and proceed properly without unnecessary delays in the scheduled chemotherapy treatments.
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Referências
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